Table 4 Drugs implicated in veno-occlusive disease/sinusoidal obstruction syndrome
6-Mercaptopurine
6-Thioguanine
Actinomycin D
Azathioprine
Busulfan*
Cytosine arabinoside
Cyclophosphamide*
Dacarbazine
Gemtuzumab-ozogamicin
Melphalan*
Oxaliplatin
Urethane

  • The drugs listed are those with the most clear-cut association with sinusoidal obstruction syndrome.

  • *Seen only in the context of high-dose conditioning regimens for haematopoietic stem cell transplantation