Table 1 Baseline characteristics (means and percentages) and univariate HR of relapse
All patients (SD) (n = 101)Relapsers (SD) (n = 37)Non-relapsers (SD) (n = 64)HR (95% CI)p Value
Age (years)33.6 (12.9)33.4 (12.5)33.7 (13.2)0.99 (0.97 to 1.02)0.64
Gender (F:M)60:4122:1538:260.89 (0.5 to 1.7)0.73
CDAI baseline66 (38.9)67 (41.2)66 (37.9)1.00 (0.99 to 1.01)0.73
Disease duration (months)90 (82.4)95.8 (93.4)86.9 (76.0)1.00 (1.00 to 1.00)0.86
Duration remission (months)11 (8.2)10.3 (7.8)11.8 (8.4)0.98 (0.94 to 1.02)0.33
Number of prior relapses4.1 (3.9)4.1 (3.8)4.0 (4.0)1.00 (0.92 to 1.09)0.98
Extraintestinal disease (%)2832251.4 (0.7 to 2.9)0.31
Previous resection (%)1619141.4 (0.6 to 3.2)0.42
Disease behaviour (%)
    Fistulising2227191.5 (0.7 to 3.1)0.26
    Inflammatory7168730.8 (0.4 to 1.6)0.54
    Stricturing7580.6 (0.2 to 2.6)0.53
Disease site (%)
    Ileitis3032281.1 (0.5 to 2.2)0.80
    Ileocolitis3827440.6 (0.3 to 1.2)0.16
    Colitis3241281.5 (0.8 to 2.9)0.22
Perianal fistula (%)1414140.9 (0.3 to 2.2)0.8
Medications (%)
    None2430201.4 (0.7 to 2.8)0.36
    5-ASA5251530.95 (0.5 to 1.8)0.87
    Purine analogues2316270.6 (0.26 to 1.5)0.28
    Methotrexate130
Smoking (%)3127330.8 (0.4 to 1.7)0.59
OC (%); n = 60
    Current3532370.8 (0.3 to 1.9)0.60
  • 5-ASA, 5-aminosalicylic acid; CDAI, Crohn’s Disease Activity Index; F, female; M, male; OC, oral contraceptive.