Table 2 Relationship between risk of non-cardia gastric cancer and pepsinogen I/II, smoking, GORD symptoms and H pylori sero-status
UnivariateMultivariate
Odds ratio (95% CI)p valueOdds ratio (95% CI)p value
PG ratio quintiles
    5th: 5.125–7.4451.001.00
    4th: 3.607–4.7933.11 (0.62 to 15.58)0.1683.50 (0.45 to 27.37)0.233
    3rd: 2.707–3.5604.77 (1.07 to 21.21)0.0406.48 (0.78 to 54.01)0.084
    2nd: 2.092–2.7017.75 (1.81 to 33.16)0.0069.08 (1.10 to 75.29)0.041
    1st: 0.189–2.01115.76 (3.92 to 63.43)0.00021.47 (2.90 to 158.76)0.003
Smoking
    Non-smoker1.001.00
    Ever smoker2.22 (1.11 to 4.46)0.0255.83 (2.11 to 16.11)0.001
GORD symptoms
    <1 time per week1.001.00
    1–2 times per week0.44 (0.20 to 0.96)0.0390.31 (0.11 to 0.85)0.023
    >2 times per week0.44 (0.17 to 1.10)0.0790.91 (0.18 to 4.64)0.913
H pylori sero-status
    Negative1.001.00
    Positive2.22 (1.11 to 4.46)0.0251.53 (0.57 to 4.14)0.401