Table 3 Histological responses of pegylated interferon α-2a and standard interferon α-2a, with or without a sustained virological response
Pegylated interferon α-2a (n = 20)Standard Interferon α-2a (n = 21)p Value
Change in inflammation score−3.2 (3.4)−1.7 (2.6)0.14
Change in fibrosis score−0.6 (0.7)−0.3 (0.6)0.28
Change in total score−3.7 (3.8)−2.0 (2.9)0.13
Percentage decrease of total score ⩾270430.12
With SVR (n = 15)Without SVR (n = 26)p Value
Change in inflammation score−4.9 (2.5)−1.0 (2.4)<0.001
Change in fibrosis score−0.8 (0.6)−0.2 (0.6)0.004
Change in total score−5.7 (2.5)−1.2 (2.7)<0.001
Percentage decrease of total sore ⩾29331<0.001

  • Values are given as the mean (SD).