Table 1 Association analysis of single nucleotide polymorphisms in PARD3 and MAGI2 in gluten-sensitive enteropathy
GSE casesControlsp Value by cohort
Allele countsMAFAllele countsMAF
MajorMinorMajorMinor
PARD3rs10763976
Dutch41743951.351040244.10.0024
Dutch extra controls41743951.3101478243.52.0×10−4
UK71774951.11221110547.50.032
Pooled Dutch + UK1134118851.22235188745.86.4×10−5
PARD3rs4379776
Dutch53831637.063627630.30.0027
Dutch extra controls53831637.0123356131.30.0034
UK90655638.0149681435.20.082
Pooled Dutch + UK144487237.72729137533.50.0016
MAGI2rs6962966
Dutch39745953.649441845.80.0011
Dutch extra controls39745953.696084046.78.0×10−4
UK74472449.31235107746.60.100
Pooled Dutch + UK1141118350.92195191746.67.6×10−4
MAGI2rs9640699
Dutch48437243.557433837.10.0061
Dutch extra controls48437243.5111568538.10.0076
UK91556538.2142188338.30.920
Pooled Dutch + UK139993740.12536156838.20.110
MAGI2rs1496770
Dutch46439245.855036239.70.0095
Dutch extra controls46439245.8106373941.00.0198
UK85258240.6133992340.80.895
Pooled Dutch + UK131697442.52402166240.90.170
  • GSE, gluten-sensitive enteropathy; MAF, minor allele frequency.