Table 2 Association analysis of single nucleotide polymorphisms in PARD3 and MAGI2 in inflammatory bowel disease
IBD combinedIBD casesControlsp Value by cohort*
Allele countsMAFAllele countsMAF
MajorMinorMajorMinor
PARD3rs10763976
IBD118895444.5101478243.50.540
Crohn’s disease64352544.9101478243.50.460
Ulcerative colitis54542944.0101478243.50.800
PARD3rs4379776
IBD143570933.1123356131.30.220
Crohn’s disease79637031.7123356131.30.800
Ulcerative colitis63933934.7123356131.30.068
MAGI2rs6962966
IBD1060108050.596084046.70.0174
Crohn’s disease59556748.896084046.70.260
Ulcerative colitis46551352.596084046.70.0036
MAGI2rs9640699
IBD130784339.2111568538.10.460
Crohn’s disease72244838.3111568538.10.900
Ulcerative colitis58539540.3111568538.10.240
MAGI2rs1496770
IBD67045240.3106373941.00.700
Crohn’s disease33923140.5106373941.00.840
Ulcerative colitis33122140.0106373941.00.680
  • *Due to technical problems, the second part of the IBD cohort failed for rs1496770; we can therefore only show the results of the first part of the cohort (IBD n = 588, Crohn’s disease n = 298, ulcerative colitis n = 290).

  • IBD, inflammatory bowel disease; MAF, minor allele frequency.