Clinico-pathological characteristic | Categorisation | n (%) | Negative | MIA2 IR | p* | |
Score 1+ | Score 2+ | |||||
Age at diagnosis | ||||||
<60 years | 39 (45.9) | 16 | 19 | 4 | 0.217 | |
⩾60 years | 46 (54.1) | 12 | 24 | 10 | ||
Gender | ||||||
Female | 16 (18.8) | 9 | 6 | 1 | 0.095 | |
Male | 69 (81.2) | 19 | 37 | 13 | ||
Tumour stage | ||||||
pT1 | 13 (15.3) | 2 | 4 | 7 | 0.036 | |
pT2 | 25 (29.4) | 10 | 12 | 3 | ||
pT3 | 41 (48.2) | 13 | 24 | 4 | ||
pT4 | 3 (3.5) | 1 | 2 | 0 | ||
nd | 3 (3.5) | 2 | 1 | 0 | ||
Histological grade | ||||||
G1 | 29 (34.1) | 12 | 14 | 3 | 0.407 | |
G2 | 48 (56.5) | 12 | 26 | 10 | ||
G3 | 8 (9.4) | 4 | 3 | 1 | ||
Aetiology | ||||||
HBV | 9 (10.6) | 5 | 4 | 0 | 0.131 | |
HCV | 7 (8.2) | 0 | 6 | 1 | ||
Alcohol | 34 (40.0) | 10 | 19 | 5 | ||
Others | 3 (3.5) | 2 | 0 | 1 | ||
Unknown | 32 (37.6) | 11 | 14 | 7 | ||
Tumour size | ||||||
⩽5 cm | 36 (42.4) | 10 | 18 | 8 | 0.323 | |
>5 cm | 30 (35.3) | 9 | 18 | 3 | ||
nd | 19 (22.4) | 9 | 7 | 3 | ||
Proliferation rate (MIB1 index) | ||||||
⩽5% | 40 (47.1) | 7 | 23 | 10 | 0.008 | |
>5% | 45 (52.9) | 21 | 20 | 4 |
*Fisher’s exact test (two-sided); bold face representing p values <0.05.
nd, no data available; IR, immunoreactivity.