Table 1 MIA2 immunoreactivity (IR) in HCC tissue of 85 patients in relation to clinico-pathological characteristics and proliferation rate
Clinico-pathological characteristicCategorisationn (%)NegativeMIA2 IRp*
Score 1+Score 2+
Age at diagnosis
<60 years39 (45.9)161940.217
⩾60 years46 (54.1)122410
Gender
Female16 (18.8)9610.095
Male69 (81.2)193713
Tumour stage
pT113 (15.3)2470.036
pT225 (29.4)10123
pT341 (48.2)13244
pT43 (3.5)120
nd3 (3.5)210
Histological grade
G129 (34.1)121430.407
G248 (56.5)122610
G38 (9.4)431
Aetiology
HBV9 (10.6)5400.131
HCV7 (8.2)061
Alcohol34 (40.0)10195
Others3 (3.5)201
Unknown32 (37.6)11147
Tumour size
⩽5 cm36 (42.4)101880.323
>5 cm30 (35.3)9183
nd19 (22.4)973
Proliferation rate (MIB1 index)
⩽5%40 (47.1)723100.008
>5%45 (52.9)21204
  • *Fisher’s exact test (two-sided); bold face representing p values <0.05.

  • nd, no data available; IR, immunoreactivity.