Table 2 Characteristics of 312 symptomatic reflux episodes in the supine and upright position in 20 patients with persisting symptoms on proton pump inhibitors
Supine (n = 30)Upright (n = 282)p value*
Pure liquid reflux (%)0 (0–58.7)43.4 (17.9–65.0)0.122
Proximal reflux events (%)0 (0–0)48.3 (17.5–71.7)0.009
Reflux bolus clearance time (s)10.4 (6.8–104.0)10.4 (6.2–13.1)0.310
Bolus burden (s)87.5 (32.8–456.3)59.9 (11.1–115.7)0.176
Nadir pH4.7 (0.9–5.1)5.5 (4.3–5.9)0.116
Acid reflux (%)0 (0–0)1.1 (0–50.6)0.374
Acid burden (s)0 (0–165.7)0 (0–0)0.273
Acid clearance time (s)5.5 (0–47)3.5 (0–17)0.655
Preceding acid reflux (%)0 (0–0)18.3 (0–64.9)0.060
Preceding weakly acidic reflux (%)0 (0–84.2)92.5 (68.3–100)0.003
  • Values are medians (interquartile range).

  • *Wilcoxon signed rank test.