Table 3 Summary of studies of chromosomal instability status and colorectal cancer progression-free survival

Reference	Ethnic origin	Study size	Stage	Clinical trial	Site	Ploidy test	DNA index cut-off
Armitage et al, 1991130	White Caucasian	236	I–IV	n	CRC	fc	1.1
Bottger et al, 1992131	White Caucasian	68	I–III	n	Rectum	fc	n/s
Chen et al, 2002133	Asian	666	I–III	n	CRC	fc	n/s
Cosimelli et al, 1998132	White Caucasian	120	I–III	n	CRC	fc	n/s
Costa et al, 1997134	White Caucasian	104	IV	n	CRC	fc	1.0
Hixon et al, 1995135	White Caucasian	52	I–III	n	CRC	fc	n/s
Kouri et al, 1990136	White Caucasian	143	I–IV	n	CRC	fc	1.0
Lammering et al, 2000141	White Caucasian	103	I–III	n	Rectum	fc	n/s
Michel et al, 2000137	White Caucasian	38	II–III	n	CRC	fc	n/s
Moran et al, 1993138	White Caucasian	138	I–III	n	Rectum	fc	n/s
Pietra et al, 1998139	White Caucasian	98	I–IV	n	CRC	fc	1.0
Lin et al, 2003142	Asian	146	I–IV	n	CRC	fc	1.0
Sampedro et al, 1999143	White Caucasian	88	I–III	n	CRC	fc	1.1
Tomoda et al, 1993140	Asian	100	I–III	n	CRC	fc	n/s

CRC, combined analysis for colorectal cancers; fc, flow cytometry; n, no; n/s, not stated in report; y, yes.