Table 1 Inflammatory parameters, haematology and overall antibody levels after rituximab therapy*
Parameter (normal range) Day 1Day 8Day 15Day 22Day 29Day 44Day 54Day 114Day 165
C-reactive protein (<10 mg/l)7859924<55
Sedimentation rate (2–20 mm/h)2424342512
Serum orosomucoid† (0.83–1.08 g/l)1.111.041.021.410.930.80
Haemoglobin‡ (7.0–10.0 mmol/l)7.77.17.07.27.37.47.17.17.5
Leukocytes (3.0–10.0×109/l)6.75.36.45.39.010.18.15.56.0
Thrombocytes (120–400×109/l)330321341367343374399363289
Immunoglobulin A (0.70–3.65 g/l)1.751.791.75
Immunoglobulin G (6.9–15.7 g/l)12.811.411.9
Immunoglobulin M (0.55–2.30 g/l)1.271.081.12
  • *Rituximab was given at days 1, 8, 15 and 22. Normal ranges are given in the parentheses.

  • †The given orosomucoid levels were measured on stored samples. The patient’s primary disease (Graves’ disease) and her anti-thyroid drug therapy may have affected the orosomucoid levels.

  • ‡Iron supplementation therapy was initiated at day 113.