Table 2 Correlation of specific and global symptom improvement
StudyTime pointsPrimary end point and symptom scoringImprovement in primary end pointSpecific symptoms correlating with primary end point
Dear 2005Last 7 days flagyl or fibre reductionComposite score, 6 symptoms38% vs 33%Bloating
Wind
Sharara 200610 days post-rifaximin or placeboGlobal improvement, 15 symptoms29% vs 12%Bloating
Pimentel 200610 week period post-rifaximin or placeboGlobal improvement, 4 symptoms36% vs 21%Bloating
Di Stephano 200010 days post-rifaximin or placeboGlobal improvement, 5 symptoms44% vs 2%Flatus
Abdominal girth