| n | TRPV1 | SP | PGP9.5 | c-kit | CD3 | CD4 | |
| IBS | 23 | 3.2 (2.2–5.1) | 2.3 (0.7–3.1) | 5.0 (3.2–6.1) | 4.0 (2.9–5.6) | 8.7 (5.9–12.1) | 1.0 (0.5–3.8) |
| Control | 22 | 0.9 (0.5–2.1) | 0.8 (0.5–1.5) | 2.7 (1.7–3.8) | 2.9 (1.9–3.9) | 5.4 (3.9–7.9) | 1.0 (0.3–1.8) |
| Ratio of medians IBS:control | – | 3.56 | 2.96 | 1.86 | 1.36 | 1.60 | 0.98 |
| p Value | – | <0.0001 | 0.01 | 0.002 | 0.02 | 0.03 | 0.29 |
Values are medians with interquartile range in parentheses. TRPV1 is expressed as fibres/mm2, and the other immunoreactivities as percentage area. Significance of differences between IBS and controls was determined by Mann–Whitney U test.
IBS, irritable bowel syndrome; PGP, protein gene product; SP, substance P; TRPV1, transient receptor potential vanilloid type-1.