Table 3 Multivariate logistic regression analysis of risk factors for oesophagitis (excluding Barrett’s oesophagus) in patients evaluated for gastro-oesophageal reflux disease
Risk factorOR (95% CI)p Value
Hiatus hernia3.621 (2.263 to 5.794)<0.001
DGOR exposure >first quartile2.245 (1.371 to 3.677)0.0014
DGOR exposure >second quartile2.440 (1.620 to 3.677)<0.001
DGOR exposure >third quartile2.511 (1.569 to 4.019)<0.001
Supine DGOR exposure >first quartile2.245 (1.371 to 3.677)0.0014
Supine DGOR exposure >second quartile2.458 (1.632 to 3.703)<0.001
Supine DGOR exposure >third quartile2.820 (1.755 to 4.530)<0.001
BMI >first quartile2.245 (1.371 to 3.677)0.0014
BMI >second quartile1.731 (1.156 to 2.590)0.0082
BMI >third quartile1.788 (1.125 to 2.842)0.0173

  • Cut-off points are given at 25% of population intervals for DGOR exposure or BMI. The referent is the population below the cut-off level. Cut-offs at the first, second and third quartile were 0.6%, 4.4% and 17.0% of time, respectively, for DGOR, and 22, 25 and 28 kg/m2, respectively, for BMI.

  • BMI, body mass index; DGOR, duodeno-gastro-oesophageal reflux.