Table 5 Multivariate logistic regression analysis of risk factors for high grade oesophagitis compared with low grade oesophagitis (excluding Barrett’s) in patients evaluated for gastro-oesophageal reflux disease
Risk factorOR (95% CI)p Value
Acid exposure >first quartile2.408 (0.537 to 10.789)0.377
Acid exposure >second quartile3.179 (1.007 to 10.038)0.043
Acid exposure >third quartile5.678 (2.006 to 16.074)0.001
Upright acid exposure >first quartile2.408 (0.537 to 10.789)0.377
Upright acid exposure >second quartile3.179 (1.007 to 10.038)0.043
Upright acid exposure >third quartile7.609 (2.572 to 22.511)0.0002

  • Cut-off points are given at 25% of population intervals for acid. Cut-offs at the first, second and third quartile for acid exposure were 0.6%, 2.2% and 7.1% of time, respectively.