Table 6 Comparison of pH and Bilitec measurements in gastro-oesophageal reflux disease patients with and without Barrett’s oesophagus
No Barrett’sBarrett’sp Value
Number39230
Age46.7 (0.7)49.4 (2.8)NS
Body mass index25.1 (0.2)26.3 (0.7)NS
Smoking (%)23%30%NS
Alcohol use (%)28%48%<0.05
Helicobacter (%)20%3%<0.05
Hiatus hernia (%)36%48%NS
Lower oesophageal sphincter pressure17.4 (0.5)11.5 (1.3)<0.05
Normal peristalsis86%79%NS
Total time acid reflux
No. of reflux episodes41 (14–82)92 (43–206)<0.001
Total reflux episodes >5 min1 (0–3)3 (1–10)<0.001
% pH<42.2 (0.6–7.1)7.8 (2.8–17.3)<0.001
Upright position acid reflux
No. of reflux episodes32 (11–66)75 (35–135)<0.001
Total reflux episodes >5 min0 (0–2)1 (0–6)<0.01
% pH<42.7 (0.6–7.8)10.9 (4.1–20.2)<0.001
Supine position acid reflux
No. of reflux episodes3 (0–15)15 (1–34)<0.01
Total reflux episodes >5 min0 (0–1)2 (0–3)<0.001
% pH<40.2 (0–3.8)7.7 (0.2–17.8)<0.005
Total time DGOR
No. of reflux episodes14 (4–35)41 (19–67)<0.001
Total reflux episodes >5 min2 (0–5)6 (2–12)<0.001
% bile absorbancy >0.144.4 (0.6–16.7)27.4 (12.1–40.4)<0.001
Upright position DGOR
No. of reflux episodes11 (2–29)27 (13–39)<0.005
Total reflux episodes >5 min1 (0–4)5 (1–8)<0.001
% bile absorbance >0.145.3 (0.7–19.6)26 (7.9–43.3)<0.001
Supine position DGOR
No. of reflux episodes0 (0–6)5 (0–19)<0.01
Total reflux episodes >5 min0 (0–2)1 (0–4)<0.01
% bile absorbance >0.140 (0–13.5)14.3 (0–57.1)<0.05
  • The periods are subdivided into total time, upright and supine position. The values are given in means (SD) or mean (IQR) and compared with the Mann–Whitney test or χ2 test. DGOR, duodeno-gastro-oesophageal reflux; NS, not significant.