Table 7 Multivariate logistic regression analysis of pH and Bilitec measurements in gastro-oesophageal reflux disease patients with and without Barrett’s oesophagus
Risk factorOR (95% CI)p Value
Male sex2.765 (1.170 to 6.533)0.02
Acid exposure >first quartile3.542 (1.234 to 10.165)0.0143
Acid exposure >second quartile3.687 (1.766 to 7.696)<0.001
Acid exposure >third quartile5.110 (2.657 to 9.826)<0.001
Upright acid exposure >first quartile3.542 (1.234 to 10.165)0.0143
Upright acid exposure >second quartile4.266 (1.991 to 9.141)<0.001
Upright acid exposure >third quartile5.110 (2.657 to 9.826)<0.001
No. of acid episodes >5 min>first quartile4.048 (1.507 to 10.873)<0.01
No. of acid episodes >5 min>second quartile4.423 (1.270 to 15.411)<0.05
No. of acid episodes >5 min>third quartile6.782 (1.810 to 25.407)<0.005
DGOR exposure >first quartile3.038 (0.090 to 10.250)0.0740
DGOR exposure >second quartile3.738 (1.477 to 9.463)0.0045
DGOR exposure >third quartile4.176 (1.886 to 9.243)0.0008
Upright DGOR exposure >first quartile4.409 (1.026 to 18.949)0.0359
Upright DGOR exposure >second quartile3.738 (1.477 to 9.463)0.0045
Upright DGOR exposure >third quartile4.929 (2.208 to 11.004)<0.001
  • Cut-offs at the first, second and third quartile were 0.6%, 4.9% and 20.1% of time, respectively, for DGOR, and 0.6% 2.4% and 7.5% of time, respectively, for acid exposure.

  • DGOR, duodeno-gastro-oesophageal reflux.