Table 5 Costs, QALYs and C/E ratios associated with four follow-up strategies for HCWs occupationally exposed to HCV according to low and high risk of HCV transmission
StrategyCosts per HCW (€)QALYsIncremental C/E ratio
Low HCV transmission risk
Baseline-US77.7023.2498
European125.6023.2551Weakly dominated*
Alternative-US149.7023.2616€6102
French152.0023.2501Strongly dominated†
High HCV transmission risk
European525.0023.1870
Alternative-US540.3023.2090€695
French550.7023.1850Strongly dominant†
Baseline-US740.6023.0830Strongly dominant†
  • *A weakly dominated strategy indicates a higher incremental C/E ratio than that of a more effective alternative strategy—that is, i.e. the incremental C/E ratio of the European strategy vs the baseline-US is higher than the incremental C/E ratio of the alternative-US strategy vs the European strategy (with low HCV transmission risk).

  • †A strongly dominated strategy indicates a higher cost than that of a more effective alternative strategy—that is, the French strategy is associated with a higher cost and a lower utility compared with the alternative-US strategy (with low HCV transmission risk), and the French and baseline-US strategies are associated with higher costs and lower utilities compared with the European strategy (with high HCV transmission risk).

  • C/E, cost-effectiveness; HCV, hepatitis C virus; HCW, healthcare worker; QALY, quality-adjusted life year.