Table 4 Multivariate logistic regression analysis on factors associated with possible and probable cirrhosis
ParameterPossible cirrhosisProbable cirrhosis
OR (95% CI)p ValueOR (95% CI)p Value
Male gender1.8 (1.4 to 2.4)<0.0011.6 (1.1 to 2.4)0.02
Age>40 years1.8 (1.4 to 2.4)<0.0012.1 (1.3 to 3.1)0.001
Obesity (BMI⩾25 kg/m2)1.4 (1.1 to 1.9)0.021.3 (0.9 to 2.0)0.14
Metabolic syndrome1.6 (1.1 to 2.4)0.0081.7 (1.1 to 2.6)0.03
Albumin<40 g/l4.2 (2.7 to 6.4)<0.0013.3 (2.1 to 5.2)<0.001
Bilirubin>15 μmol/l1.2 (0.9 to 1.5)0.221.3 (0.9 to 1.8)0.17
AP>ULN2.4 (1.6 to 3.4)<0.0012.9 (2.0 to 4.4)<0.001
ALT>ULN2.8 (2.2 to 3.7)<0.0012.9 (2.0 to 4.1)<0.001
HBV DNA>2 log10 copies/ml1.1 (0.7 to 1.6)0.650.9 (0.6 to 1.7)0.91
  • AP, alkaline phosphatase; ALT, alanine aminotransferase; BMI, body mass index; CI, confidence interval; HBV, hepatitis B virus; OR, odds ratio; ULN, upper limit of normal.