| Characteristic | All patients (n = 200) | Patients with PRSS1 mutations (n = 135) | Patients without detected PRSS1 mutation (n = 65‡) | p Value§ |
| Ductal lesions (%) (md = 15) | 117 (63) | 79 (63) | 38 (63) | NS |
| Pancreatic calcifications (%) (md = 14) | 113 (61) | 78 (62) | 35 (59) | NS |
| Age at diagnosis of pancreatic calcifications* | 23 (3–73) | 24 (3–57) | 23 (6–73) | NS |
| Venous thrombosis† (%) (md = 3) | 11 (6) | 9 (7) | 2 (3) | NS |
| Pseudocysts (%) (md = 5) | 44 (23) | 32 (25) | 12 (18) | NS |
*Median and (range).
†Thrombosis of the splenic vein or/and the portal vein.
‡Including nine patients, deceased before 1996, in whom the PRSS1 mutation could not be searched for.
§The Kruskall–Wallis test for continuous data and the χ2 test or Fisher’s exact test for categorical data were used.
CP, chronic pancreatitis; md, missing data; NS, not significant; PRSS1, cationic trypsinogen gene.