Liver biopsy features (n = 29)
| Histological finding | Number (%) |
| Steatosis score | |
| 0, Minimal (<5%) | 0 |
| 1, Mild (>5–33%) | 5 (17.2) |
| 2, Moderate (>33% and 66%) | 11 (37.9) |
| 3, Severe (>66%) | 13 (44.8) |
| Lobular inflammation score | |
| 0, No foci | 1 (3.4) |
| 1, Mild | 26 (89.7) |
| 2, Moderate | 1 (3.4) |
| 3, Severe | 1 (3.4) |
| Hepatocellular ballooning | |
| 0, None | 24 (82.8) |
| 1, Few | 5 (17.2) |
| 2, Prominent | 0 |
| NAFLD activity score | |
| 1–2 | 5 (17.2) |
| 3–4 | 20 (70) |
| 5 or more | 4 (13.8) |
| Fibrosis | |
| Stage 0 | 12 (41.3) |
| Stage 1 Perisinusoidal or periportal | |
| 1A Delicate perisinusoidal | 3 (10.3) |
| 1B Dense perisinusoidal | 1 (3.5) |
| 1C Periportal only | 2 (6.9) |
| Stage 2 Perisinusoidal and periportal | 5 (17.2) |
| Stage 3 Bridging fibrosis | 4 (13.8) |
| Stage 4 Cirrhosis | 2 (6.9) |
| Mallory’s hyaline | 4 (13.8) |
Liver biopsy features were graded and staged according to the scoring system proposed by Kleiner et al.31 The grade of steatosis (0–3), lobular inflammation (0–3), and ballooning (0–2) were then combined to determine the non-alcoholic fatty liver disease (NAFLD) activity score (0–8) as proposed.31