Risk assessments of clinical parameters for advanced fibrosis
| Characteristics | Simple steatosis and NASH fibrosis 0–2 (n = 76) n (%) | NASH fibrosis 3–4 (n = 46) n (%) | p Value | OR (95% CI) |
| Age ⩾50 years | 45 (59) | 37 (80) | 0.016 | 2.8 (1.2 to 6.7) |
| Female gender | 42 (55) | 33 (72) | 0.070 | 2.1 (0.9 to 4.5) |
| Body mass index ⩾28 kg/m2 | 24 (32) | 15 (33) | 0.906 | 1.0 (0.5 to 2.3) |
| Hypertension | 18 (24) | 18 (39) | 0.070 | 2.1 (0.9 to 4.6) |
| Diabetes | 21 (28) | 24 (52) | 0.007 | 2.9 (1.3 to 6.1) |
| Hyperlipidaemia | 52 (68) | 20 (43) | 0.007 | 0.4 (0.2 to 0.8) |
| AST/ALT ⩾0.8 | 16 (21) | 27 (59) | <0.0001 | 5.3 (2.4 to 11.9) |
| Platelets <200×109 cells/l | 25 (33) | 36 (78) | <0.0001 | 7.3 (3.1 to 17.1) |
| Albumin <4.1 g/dl | 24 (32) | 32 (70) | <0.0001 | 5.0 (2.2 to 10.9) |
ALT, alanine aminotransferase; AST, asparate aminotransferase; NASH, non-alcoholic steatohepatitis.