Table 1 Baseline characteristics of the 3669 study subjects
CharacteristicNo. of subjects (%)
Male2483 (67.7)
Smoker416 (11.3)
Drinks alcohol (at least once per week)2219 (60.5)
Chronic illnesses
    Cardiac47 (1.3)
    Pulmonary92 (2.6)
    Hepatic501 (13.7)
Peptic ulcer648 (17.7)
Cholesterol ⩾200 mg/dl314 (8.6)
Hyperuricaemia* and/or history of gout283 (7.7)
Metabolic syndrome498 (13.6)
    Enlarged waist circumference1239 (33.8)
    Hypertension or blood pressure ⩾130/85 mm Hg559 (15.2)
    Diabetes or fasting glucose ⩾110 mg/dl198 (5.4)
    HDL-C <40 mg/dl1678 (45.7)
    Triglycerides ⩾150 mg/dl908 (24.7)
Exercise, number of times per week
    ⩾51013 (27.6)
    3–41585 (43.2)
    ⩽21071 (29.2)
Sleep quality
    Good1600 (43.6)
    Fair1564 (42.6)
    Poor505 (13.8)
Symptoms of GORD413 (11.3)
Short-term use of PPI or H2RA587 (11.4)†
  • GORD, gastro-oesophageal reflux disease; H2RA, histamine-2 receptor antagonist; HDL-C, high-density lipoprotein cholesterol; PPI, proton pump inhibitor.

  • *Serum uric acid concentration >7.5 mg/dl.

  • †From 5145 transition periods.