Table 2 Expression of genes found to be upregulated in infiltrative tumours and confirmed with the Welch t test for data with unequal variances
Gene nameHGNC gene symbolGene IDEMBL accession numberFold change*p Value (95% CI)
Microfibrillar protein 2 mRNA, partial cds.AF2060204.40.007 (0.19 to 0.92)
mRNA for IgM light chain variable region, BO3-VLX878903.50.006 (0.09 to 0.48)
Deleted in malignant brain tumours DMBT1 17553.10.009 (0.81 to 4.87)
Cyclin D2 CCND2 8942.90.002 (0.73 to 2.94)
Zinc finger and SCAN containing 18 ZSCAN18 659822.80.011 (0.13 to 0.88)
Endothelin 1 EDN1 19062.70.014 (0.16 to 1.27)
Sperm associated antigen 18 SPAG16 795822.70.004 (0.10 to 0.46)
Amyloid lambda light chain variable region, partial cds.AF0269232.50.044 (0.01 to 0.64)
Transmembrane 4 superfamily member 5 TM4SF5 90322.40.049 [0.002 to 0.63)
Lectin, galactoside-binding, soluble 2 LGALS2 39572.30.041 (0.01 to 0.48)
NANUC-1 kappa light chain and part of constant region mRNA, partial cds.U503422.30.035 (0.02 to 0.54)
Homeobox B7 HOXB7 32172.30.001 [0.30 to 0.97)
Sodium dependent dicarboxylate transporter SLC13A2 90582.30.018 (0.05 to 0.50)
Carboxylesterase 2 (intestine/liver) CES2 88242.20.011 (0.03 to 0.21)
Dipeptidylpeptidase 4/CD26 DPP4 18032.20.028 (0.11 to 1.81)
Insulin receptor substrate 2 IRS2 86602.20.004 (0.24 to 1.14)
Prune homolog 2 (Drosphila) PRUNE2 1584712.20.028 (0.17 to 2.64)
Clone S12G10K myosin-reactive immunoglobulin light chain variable region mRNAAF0350352.10.013 (0.10 to 0.73)
Myotubularin related protein 11 MTMR11 109032.10.007 (0.09 to 0.51)
Flotillin 1 FLOT1 102112.0>0.001 (0.22 to 0.59)
Membrane protein, palmitoylated 1 MPP1 43542.00.031 (0.08 to 1.54)
v-src sarcoma viral oncogene homolog SRC 67141.90.001 (0.43 to 1.50)
Retinoblastoma 1 RB1 59251.90.005 (0.27 to 1.40)
Jumonji AT rich interactive domain 1A JARID1A 59271.90.013 (0.24 to 1.70)
Plectin 1, intermediate filament binding protein PLEC1 53391.90.001 (0.27 to 0.90)
Cysteine, dibasic and neutral amino acid transporters SLC3A1 65191.80.018 (0.16 to 1.55)
Poly (ADP-ribose) polymerase family (member 8) PARP8 796681.80.002 (0.24 to 0.94)
Bradykinin receptor B2 BDKRB2 6241.8<0.001 (0.10 to 0.28)
Myosin 1A MYO1A 46401.70.001 (0.07 to 0.23)
Granulysin GNLY 105781.70.037 (0.07 to 1.82)
Latexin protein LXN 569251.70.011 (0.11 to 0.70)
  • *Fold change with respect to infiltrative phenotype.

  • CI, confidence interval; EMBL, European Molecular Biology Laboratory; HGNC, HUGO (Human Genome Organisation) Gene Nomenclature Committee.