Table 3 Expression of genes found to be downregulated in infiltrative tumours and confirmed with the Welch t test for data with unequal variances
Gene nameHGNC gene symbolGene IDFold change*p Value (95% CI)
Serine protease 23 PRSS23 110983.5<0.001 (−0.81 to −0.26)
Lactate dehydrogenase B LDHB 39452.90.001 (−2.74 to −0.75)
p53 TP53 39452.50.012 (−1.15 to −0.15)
CD163 molecule-like 1 CD163L1 2833162.00.047 (−2.69 to −0.02)
Beta-parvin PARVB 297801.90.031 (−2.24 to −0.12)
Transferrin receptor TFRC 70371.9<0.001 (−1.28 to −0.44)
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ST6GAL1 64801.80.042 (−1.46 to −0.29)
Defensin, alpha 6 DEFA6 16711.80.020 (−3.49 to −0.33)
  • *Fold change with respect to infiltrative phenotype.

  • CI, confidence interval; HGNC, HUGO (Human Genome Organisation) Gene Nomenclature Committee.