Table 2 Changes in the gut microbiota upon administration of prebiotics impacts on portal plasma gut peptides

Gut peptide	Ob-CT	Ob-Cell	Ob-Pre
GLP-1 (active) (pmol/l)	7.65^a (1.52)	7.71^a (1.62)	21.15^b (6.71)
GIP (total) (pg/ml)	207.91^a (37.76)	180.71^a (27.53)	114.02^b (16.92)
Pancreatic polypeptide (pg/ml)	68.07^a (8.45)	75.94^a (6.56)	50.05^b (2.67)
Amylin (active) (pg/ml)	358.87^a (36.12)	364.99^a (45.07)	504.90^b (58.34)
GLP-2 (ng/ml)	0.56^a (0.06)	0.62^a (0.04)	0.75^b (0.05)

Data are mean (SEM).
Data with different superscript letters are significantly different at p<0.05, according to the post hoc ANOVA statistical analysis.
CT, Cell and Pre, respectively, refer to the selected ob/ob mice, fed a normal diet, non-prebiotic control diet or prebiotic diet. GIP, glucose-dependent insulinotropic polypeptide; GLP, glucogon-like peptide.