Table 1 TIC characteristics of human pancreatic adenocarcinoma cell lines
AsPC-1MIA-PaCa2Capan-1BxPc-3
ATCC noCRL-1682CRL-1420HTB 79CRL-1687
SourceAscitesPrimary tumourLiver metastasisBiopsy primary tumour
Degree of differentiationModerate–poorPoorModerateWell
Degree of resistanceHighHigh–moderateHighLow
Colony-forming capacityHighHighHighLow
Spheroid-forming capacityLowHighModerateNone
ALDH activity4%37%1%0%
Growth on nude miceYesYesYesYes, but slow
CD44+/CD24 surface expression93.5 (5.3)95.5 (3.7)95.3 (4.5)17.5 (5.7)
  • ALDH, aldehyde dehydrogenase; ATCC, American Type Culture Collection; TIC, tumour-infiltrating cell.