Odds ratios (ORs) for the probability of detection of colorectal neoplasia in screened individuals which FIT and FS in comparison with gFOBT
| Advanced neoplasia OR, (CI) | Colorectal cancer OR, (CI) | |
| gFOBT | 1 | 1 |
| FIT | 2.0 (1.3 to 3.2) | 1.8 (0.7 to 4.7) |
| FS | 7.0 (4.6 to 10.7) | 2.2 (0.8 to 6.3) |
Advanced neoplasia: adenoma ⩾10 mm, villous component (⩾25% villous) or high-grade dysplasia; colorectal cancer.
CI, confidence interval; FIT, immunochemical faecal occult blood test; FS, flexible sigmoidoscopy; gFOBT, guaiac-based faecal occult blood test.