Table 4 Genes downregulated in Nas1^−/− ileum

Accession number	Gene symbol	Gene description	Gene ontology	Fold change*	B score
Energy/metabolism
NM_009799	Car1	Carbonic anhydrase 1	Protein targeting	0.1	2.67
NM_013820	Hk2	Hexokinase 2	Glycolysis	0.5	2.28
NM_019481	Slc13a1	Solute carrier family 13, member 1	Sulfate transport	0.7	0.28
NM_007480	Arf5	ADP-ribosylation factor 5	Protein transport	0.7	1.15
NM_020049	Slc6a14	Solute carrier family 6, member 14	Amino acid metabolism	0.7	0.88
AF183960	Ccr4	Carbon catabolite repression 4-like	Rhythmic behaviour	0.8	0.52
NM_019755	Plp2	Proteolipid protein 2	Ion transport	0.8	0.20
Cell signalling
NM_009789	S100g	Calbindin 3	Signal transduction	0.6	0.32
NM_007609	Casp4	Caspase 4	Apoptosis	0.7	1.68
Cell defence/immune response
NM_009117	Saa1	Serum amyloid A1	Acute-phase response	0.5	1.24
NM_011111	Serpinb2	Serine/cysteine proteinase inhibitor, B2	Acute-phase response	0.7	1.95
U96705	Serpinb9b	Serine/cysteine proteinase inhibitor, B9b	Acute-phase response	0.7	0.89
NM_007428	Agt	Angiotensinogen	Acute-phase response	0.7	1.57
NM_009252	Serpina3n	Serine/cysteine proteinase inhibitor, A3N	Acute-phase response	0.7	1.02
NM_008768	Orm1	Orosomucoid 1	Acute-phase response	0.8	0.64
NM_023517	Tnfsf13	Tumour necrosis factor superfamily, 13	Immune response	0.8	0.27
Transcription/chromatin
M81385	LRH-1	Nuclear receptor subfamily 5, A2	Transcription regulation	0.7	0.61
NM_008329	Ifi204	Interferon, gamma-inducible protein 16	Transcription regulation	0.8	0.26