Table 2

Results of univariate analysis for predictors of clinical remission and colectomy

Clinical remissionColectomy
OR (95% CI)p ValueOR (95% CI)p Value
Female gender0.74 (0.34 to 1.59)0.570.81 (0.39 to 1.72)0.73
Age1.62 (0.75 to 3.52)0.290.47 (0.22 to 1.02)0.85
Pancolitis1.23 (0.48 to 3.16)0.851.56 (0.61 to 3.97)0.49
Disease duration0.99 (0.41 to 2.42)0.830.58 (0.25 to 1.37)0.31
Baseline Mayo score ⩾100.36 (0.15 to 0.83)0.0283.42 (1.56 to 7.51)0.004
Prednisone ⩾1 year preinfliximab0.40 (0.14 to 1.17)0.451.68 (0.69 to 4.15)0.38
Concurrent immunosuppression1.16 (0.47 to 2.88)0.921.13 (0.46 to 2.75)0.96
Baseline CRP >5 mg/l0.60 (0.21 to 1.69)0.481.94 (0.65 to 5.81)0.35
pANCA positive0.89 (0.36 to 2.16)0.790.58 (0.25 to 1.33)0.28
Antibodies to infliximab0.15 (0.06 to 0.40)<0.0012.71 (1.22 to 6.01)0.023
Detectable trough serum infliximab12.0 (4.76 to 30.26)<0.0010.13 (0.05 to 0.35)<0.001
  • Values in bold are statistically significant with a p value <0.05.

  • CRP, C-reactive protein; pANCA, perinuclear antineutrophil cytoplasmic antibody.