Variable | Number of patients | Sex F/M | Tumour location right colon/left colon/rectum/others* | Tumour stage I and II | Tumour stage III and IV | Tumour stage (unknown) | Mean age at the time of surgery (years) (range) |
Inherited CRC | |||||||
HNPCC | 42 | 16/26 | 22/11/9/0 | 28 | 13 | 1 | 49.1 (23–81) |
FAP | 13 | 6/7 | 2/3/8/0 | 6 | 7 | 0 | 46.8 (20–77) |
Sporadic CRC | |||||||
MSI | 40 | 25/15 | 35/4/1/0 | 23 | 17 | 0 | 73.7 (46–90) |
MSS | 49 | 21/28 | 7/19/23/0 | 23 | 24 | 2 | 66.3 (45–86) |
Controls | 20 | 14/6 | – | – | – | – | 66.1 years (33–87) |
IBD-associated CRC | |||||||
MSI | 13 | 5/8 | 6/3/3/1 | 6 | 5 | 2 | 48.6 (19–65) |
MSS | 36 | 16/20 | 8/5/22/1 | 16 | 18 | 2 | 50.2 (22–78) |
Controls | 27 | 10/17 | – | – | – | – | 37.7 (16–78) |
↵* Others: anastomotic relapse and perineal abcess.
CRC, colorectal cancer; F, female; M: male; FAP, familial adenomatous polyposis; HNPCC, hereditary non-polyposis colorectal cancer; IBD, inflammatory bowel disease; MSI, microsatellite unstable; MSS, microsatellite stable.