Table 1

Baseline characteristics of included patients

Patient number
12345678910
Age (years)24363334344229321930
SexFFFFFMMFFF
Disease duration (years)105153114712310
CDAI at screening442346283316337237316280255277
Baseline CDAI332341254326350266378224NA304
Disease localisationIleocolonicColonic, ileum NDColonic, ileum NDIleumIleumColonicColonic, ileum NDColonic, ileum NDNo active diseaseColonic
Perianal diseaseyny, perianal abscess (inactive)ny (inactive)ny (inactive)nny (inactive)
Extra-intestinal manifestationsArthralgiasArthralgiasnArthralgiasnncheilititis granulomatosannn
Current medical therapiesCS 50mg, AZAMTX, ADACS 10mgCS 5mgCS 40mgMTXCS 30mg, 6-MPCS 5mg, MTXNACS 5mg, MTX
Height (cm)175167174172158160187.5173157161
Weight (kg)59.368.67499.94678107.5113.250.553.1
Current smoker/smoking historyn/nn/nn/nn/yn/nn/yy/yn/nn/yn/y
Prior medical therapiesCS, AZA, IFX, MTX, CZP, ADA5-ASA, CS, AZA, IFX, MTX, ADA5-ASA, CS, ATB, AZA, IFX, MTX, CZP, ADA5-ASA, CS, 6MP, IFX, MTX, CZP, ADA5-ASA, CS, AZA, IFX, MTX, CZP, ADA, TACCS, AZA, IFX, MTX, ADA5-ASA, CS, AZA, IFX, CZP, ADA5-ASA, CS, AZA, IFX, MTX, ADA5-ASA, CS, ATB, AZA, IFX, MTX, CZP, ADA5-ASA, CS, AZA, IFX, MTX, CZP, ADA, HSCT
Prior surgeriesIleocoecal resectionnIleocoecal resectionIleocoecal resectionIleocoecal resection, colostoma on colon transversumnnnnn
  • ADA, adalimumab; 5-ASA, mesalamine; ATB, antibiotics; AZA, azathioprine; CS, corticosteroids; CZP, certoluzimab pegol; F, female; HSCT, mobilisation phase of haematopoietic stem cell transplantation; IFX, infliximab; M, male; 6-MP, 6-mercaptopurine; MTX, methotrexate; n, no; y, yes; NA, not applicable; ND, not determined; TAC, tacrolimus;