Table 2

Outcomes of levofloxacin-based and clarithromycin-based triple therapy

Eradication rateFirst line (7 days)Second line (10 days)Overall
Group A LAL n=217Group B CAL n=215p ValueGroup A CAL n=40Group B LAL n=26p ValueGroup A LAL–CAL n=217Group B CAL–LAL n=215p Value
ITT74.2% (161/217)83.7% (180/215)0.015*60% (24/40)76.9% (20/26)0.15485.3% (185/217)93% (200/215)0.01*
PP80.1% (161/201)87.4% (180/206)0.046*61.5% (24/39)80% (20/25)0.12092.5% (185/200)97.6% (200/205)0.019*
  • * χ2 test.

  • Fisher exact test.

  • CAL, clarithromycin, amoxicillin and lansoprazole; ITT, intention-to-treat; LAL, levofloxacin, amoxicillin and lansoprazole; PP, per-protocol.