Table 2

HR for death from any cause among patients with gastric cancer, according to multivariate cox regression analysis

VariableHR n (95% CI)p Value
Training set
Overall survival
High risk miRNA signature3.046 (1.246 to 7.445)0.015
Tumour stage III and IV2.962 (1.895 to 4.631)<0.0001
Relapse-free survival
High risk miRNA signature3.337 (1.298 to 8.580)0.012
Tumour stage III and IV3.811 (1.495 to 9.715)0.001
Testing set
Overall survival
High risk miRNA signature2.891 (1.066 to 7.839)0.037
Tumour stage III and IV3.283 (1.278 to 8.438)0.014
Relapse-free survival
High risk miRNA signature3.749 (1.472 to 9.550)0.006
Tumour stage III and IV3.444 (1.501 to 7.902)0.004
Validation set
Overall survival
High risk miRNA signature2.625 (1.059 to 6.504)0.037
Tumour stage III and IV3.350 (1.793 to 6.260)0.0002
Relapse-free survival
High risk miRNA signature3.044 (1.086 to 8.532)0.034
Tumour stage III and IV3.312 (1.187 to 9.246)0.022
  • Note: Variables were selected with a stepwise selection method.