Risk factors for malignant progression in Barrett's oesophagus (n=16 333)
| HR univariate | 95% CI | HR multivariate | 95% CI | |
| Sex | ||||
| Female | 1.00 | – | 1.00 | – |
| Male | 1.58 | 1.27 to 1.96 | 2.12 | 1.70 to 2.65 |
| Age | ||||
| <40 years | 1.00 | – | 1.00 | – |
| 40–49 years | 1.77 | 1.03 to 3.05 | 1.81 | 1.05 to 3.11 |
| 50–59 years | 2.56 | 1.54 to 4.30 | 2.64 | 2.90 to 3.96 |
| 60–69 years | 3.32 | 2.00 to 5.51 | 3.57 | 1.58 to 4.41 |
| 70–79 years | 8.77 | 5.27 to 14.6 | 10.0 | 5.99 to 16.7 |
| >80 years | 16.38 | 8.70 to 30.9 | 21.0 | 11.1 to 39.7 |
| Histopathology | ||||
| BO with ND | 1.00 | – | 1.00 | – |
| BE with LGD | 2.24 | 1.80 to 2.80 | 1.92 | 1.54 to 2.40 |
LGD high-grade dysplasia; ND, no dysplasia.