Fatty acid content of rectal mucosa
| Fatty acid | Placebo (n=26) | EPA-FFA (n=26) | Difference EPA-FFA–placebo | p Value | ||||
| Baseline | 6 months | Change | Baseline | 6 months | Change | |||
| (SD) | (SD) | (95% CI) | (SD) | (SD) | (95% CI) | (95% CI) | ||
| EPA | 0.73* (0.72) | 1.30 (1.09) | 0.54 (−0.06 to 1.13) | 0.97 (0.89) | 2.50 (1.98) | 1.56 (0.97 to 2.15) | 1.03 (0.18 to 1.87) | 0.018 |
| DPA | 0.75 (0.65) | 0.76 (0.66) | 0.04 (−0.20 to 0.28) | 0.64 (1.15) | 1.17 (0.69) | 0.49 (0.25 to 0.73) | 0.45 (0.11 to 0.79) | 0.010 |
| DHA | 1.39 (0.61) | 1.42 (1.05) | −0.11 (−0.46 to 0.24) | 1.92 (1.30) | 1.71 (0.94) | −0.07 (−0.42 to 0.28) | 0.04 (−0.47 to 0.55) | 0.875 |
| AA | 9.63 (2.18) | 9.88 (1.86) | 0.61 (−0.10 to 1.31) | 8.47 (1.68) | 8.82 (1.91) | −0.01 (−0.72 to 0.69) | −0.62 (−1.63 to 0.40) | 0.228 |
↵* Data are presented as the mean (%) of the total mucosal fatty acid pool.
AA, arachidonic acid; DHA, docosahexaenoic acid; DPA, docosapentaenoic acid; EPA, eicosapentaenoic acid; FFA, free fatty acid.