Table 3

A comparison of the performance of each test for the diagnosis of advanced fibrosis in 145 patients with non-alcoholic fatty liver disease (NAFLD)

TestAUROC (95% CI)Cut-offSens (%)Spec (%)PPV (%)NPV (%)
AST/ALT ratio0.83 (0.74 to 0.91)0.874784493
APRI0.67 (0.54 to 0.8)127893784
BARD score0.77 (0.68 to 0.87)289442795
FIB-4 score0.86 (0.78 to 0.94)1.3085653695
NAFLD fibrosis score0.81 (0.71 to 0.91)−1.45578583092
  • ALT, alanine aminotransferase; APRI, AST-to-platelet ratio index; AST, aspartate aminotransferase; AUROC, area under the receiver operating characteristic curve; PPV, positive predictive value; NPV, negative predictive value; Sens, sensitivity; Spec, specificity.