Prevalence of adenomas and adenomas with advanced pathology (AAPs) in familial colorectal cancer
| Study | Type of family | Age (mean) | n | Adenoma | AAP |
| Current study 2010 | 1 FDR with CRC <50 | 45–65 | 224 | 15.6% | 5.8% |
| 2 FDR with CRC at any age | 45–65 | 232 | 22.0% | 10.8% | |
| Gaglia 19955 | 2 FDR with CRC at any age | 25–77 (41) | 128 | 23.4% | |
| ≥1 FDR with CRC <50 | 25–77 (41) | 339 | 19.2% | ||
| Hunt 19986 | 1 FDR < 50 or 2 FDR CRC at any age | 40–69 | 52 | 13.5% | |
| Lindgren 20027 | 2 FDR with CRC at any age | (50.0) | 73 | 32.8% | |
| Syrigos 20028 | 2 FDR with CRC at any age | 22–75 (44) | 37 | 13.5% | |
| Dove-Edwin 20059 | 2 FDR or 1 FDR and 1 SDR, who are FDRs of each other | 45–64 | 201 | 19.4% | 4.0% |
| 1 FDR < 45 | 45–64 | 53 | 15.1% | ||
| Wark 200910 | ≥2 FDR at any age | (66.7) | 325 | 19.1% | 10.2% |
| ≥1 FDR, at least 1 CRC < 50 | (66.7) | 339 | 14.5% | 7.1% |
CRC, colorectal cancer; FDR, first-degree relative; SDR, second-degree relative.