Clinical characteristics of 23 patients with malignant transformation within hepatocellular adenoma (HCA) stratified by number of HCA and gender. Two patients (one male and one female) operated at other institutions were excluded from this analysis
| Single | Multiple | Age (years) | ||
| Associated condition | Female (n=4) | Male (n=16) | Female (n=3) | Median (range) |
| OCs>2 years | 3 | – | 2 | 37 (35–41) |
| OCs<2 years | 1 | – | 0 | 54 |
| Androgens/steroids | – | 3 | – | (20–47) |
| Fanconi's anaemia/HBV | 0 | 2 | 0 | (45–70) |
| Vascular disorders | 0 | 1 | 1 | (30–67) |
| Metabolic syndrome | 0 | 6 | 0 | 62 (52–75) |
HBV, hepatitis B virus; OCs, oral contraceptives.