Table 2

Cytokine production (pg/ml) by cultured peripheral blood and lamina propria mononuclear cells

Responder	Cytokine	Peripheral blood		Lamina propria
Responder	Cytokine	Pre	Post	Pre	Post
T cell stimulation	IL-13	594±327	265±108	690±99^*	297±58^*
	IL-10	523±176	528±178	139±58	128±53
	IFNγ	4001±1416	4955±2334	1003±185	1438±210
	IL-4	114±48	119±53	102±41	30±10
	IL-17	39±17	25±4^†	8±2^‡	6±1^§
Macrophage stimulation	IL-6	42 466±4982^¶	58 063±10 605	1644±147	1703±265
	TNFα	3439±408	3250±435	1012±172	755±220
	IL-12	279±173	196±70	33±10	67±25

Nonresponder
T cell stimulation	IL-13	350±116	393±164	542±83	510±39
	IL-10	976±491	574±206	229±119	437±236
	IFNγ	1770±599	2587±1685	1688±647	2700±1455
	IL-4	116±69	53±35	78±69	24±22
	IL-17	191±164	86±27^†	70±38^‡	70±34^§
Macrophage stimulation	IL-6	133 177±35 259^¶	117 952±35 883	1861±836	5125±3524
	TNFα	5298±1778	4429±1278	885±455	1346±456
	IL-12	165±68	86±30	26±6	20±13

↵* p=0.01 Resp LP T cell IL-13 pre versus post.
↵† p=0.006 PB Post T cell IL-17 Resp versus Nonresp.
↵‡ p=0.039 LP Pre T cell IL-17 Resp versus Nonresp.
↵§ p=0.017 Post LP T cell IL-17 Resp versus Nonresp.
↵¶ p=0.006 PB Pre Mac/APC IL-6 Resp versus Nonresp