Oesophageal squamous cell carcinoma | Gastric cardia adenocarcinoma | |||||
HR | 95% CI | pinteraction† | HR | 95% CI | pinteraction† | |
Overall | 0.86 | 0.79 to 0.93 | 0.81 | 0.73 to 0.89 | ||
Sex | ||||||
Men | 0.89 | 0.80 to 0.98 | 0.82 | 0.73 to 0.93 | ||
Women | 0.82 | 0.72 to 0.92 | 0.19 | 0.77 | 0.64 to 0.94 | 0.66 |
Age (in years) | ||||||
(<50) | 0.92 | 0.74 to 1.14 | 1.10 | 0.76 to 1.58 | ||
(50–60) | 0.89 | 0.80 to 1.00 | 0.79 | 0.69 to 0.91 | ||
(>60) | 0.80 | 0.70 to 0.91 | 0.0014 | 0.79 | 0.66 to 0.94 | <0.0001 |
Cigarette smoking† | ||||||
Never smokers | 0.91 | 0.73 to 1.13 | 0.79 | 0.62 to 1.00 | ||
Ever smokers | 0.89 | 0.79 to 1.00 | 0.89 | 0.84 | 0.73 to 0.97 | 0.41 |
0.5 | ||||||
Alcohol drinking† | ||||||
Non-drinkers | 0.87 | 0.76 to 1.00 | 0.77 | 0.66 to 0.90 | ||
Drinkers | 0.93 | 0.78 to 1.10 | 0.94 | 0.86 | 0.69 to 1.07 | 0.30 |
↵* Adjusted HRs and 95% CIs in were calculated using models stratified on age and sex, with additional adjustment for continuous age variables within each stratum, cigarette smoking, alcohol drinking, BMI, serum creatinine and serum creatinine squared.
↵† Cigarette and alcohol consumption were almost completely restricted to men, so data stratified by these exposures are not presented for women.