Cox regression model for the HR for death on home parenteral nutrition and causes of death on home parenteral nutrition, according to the indications for intestinal transplantation in candidates who completed the 5-year follow-up
| Patients deceased on HPN during the 5 years of follow-up | ||||
| Indication for intestinal transplantation | HR for death (95% CI) | p Value | Total number of deaths | Deaths related to indications for transplantation, No. (%) |
| Desmoid tumours | 7.11 (2.53 to 19.99) | <0.001 | 4 | 4 (100) |
| HPN/IF-associated liver failure | 3.38 (1.58 to 7.22) | 0.002 | 8 | 7 (87.5) |
| CVC-related thrombosis (≥2 veins) | 2.08 (0.97 to 4.46) | 0.058 | 8 | 3 (37.5) |
| Frequent/severe CVC-related sepsis | 1.09 (0.15 to 7.88) | 0.929 | 1 | 0 |
| Ultra-short bowel | 0.83 (0.25 to 2.68) | 0.763 | 3 | 2 (66.7) |
| Congenital mucosal disorders | 0.46 (0.05 to 2.93) | 0.374 | 1 | 0 |
Causes of death on home parenteral nutrition (No. of patients).
Desmoids tumours: liver failure associated to HPN/IF (1); desmoid tumour (3).
HPN/IF-associated liver failure: liver failure (5); sepsis related to central venous catheter (2); other/unknown (1).
CVC-related thrombosis (≥2 veins): liver failure associated to HPN/IF (1); sepsis related to central venous catheter (2); underlying disease (3); other/unknown (2).
Frequent/severe CVC-related sepsis: underlying disease (1).
Ultra-short bowel: liver failure associated to HPN/IF (2); other/unknown (1).
Congenital mucosal disorders: other/unknown (1).
CVC, central venous catheter; HPN, home parenteral nutrition; IF, intestinal failure.