Table 5

Diagnostic performance of enhanced liver fibrosis (ELF) and biopsy predicting liver-related clinical outcomes at 6 years

ELF threshold	Sensitivity	Specificity	PPV	NPV	LR+	LR−	DOR
8.64	95	55	27	98	2.11	0.10	21.3
8.89	91	66	32	97	2.69	0.14	19.6
9.49	84	81	44	97	4.45	0.20	22.1
9.88	76	86	48	95	5.43	0.26	20.9
10.25	67	89	52	94	6.21	0.37	16.9
11.15	40	95	58	90	7.85	0.63	12.4
12.99	16	99	69	87	12.9	0.85	15.2

Biopsy stage	Sensitivity	Specificity	PPV	NPV	LR+	LR−	DOR
1	96	28	18	97	1.32	0.16	8.6
2	87	53	24	96	1.85	0.24	7.7
3	85	66	29	96	2.5	0.23	11.2
4	70	77	34	94	3.1	0.39	8.1
5	62	89	47	93	5.4	0.43	12.4
6	49	91	48	92	5.6	0.56	10.0

DOR, diagnostic odds ratio; LR, likelihood ratio; NPV, negative predictive value; PPV, positive predictive value.