Table 1

Baseline demographic clinical, and laboratory characteristics on the first day of treatment for patients with severe alcoholic hepatitis (AH) pooled according to random assignment to control or corticosteroid treatment

Patients allocated to non-corticosteroid groupPatients allocated to corticosteroid groupp Value
Number of patients197221
Male gender (%)71.6%66.5%0.3
Median (95% CI) age (years)47 (46 to 50)47 (45 to 50)0.81
Range25–7125–77
Median (95% CI) prothrombin time (s)*16 (15.5 to 16.5)16 (15.5 to 16.5)0.7
Range11–3211.2–31
Median (95% CI) bilirubin (μmol/l)*295 (256.7 to 361)295.8 (254 to 343)0.58
Range30–824.558–786
Median (95% CI) Maddrey function*48.5 (45.5 to 51.3)48.4 (46.5 to 52.5)0.62
Range11.2–131.315.3–134.5
Median (95% CI) serum creatinine (μmol/l)*94.5 (88.4 to 103)91 (88.4 to 106)0.98
Range40–945.936–1774
Median (95% CI) albumin (g/l)*25 (24.1 to 26)26 (26 to 27)0.14
Range13–44.414–38.4
Median (95% CI) AST (IU/l)*95.5 (88 to 105)100 (89 to 109)0.99
Range13–46221–480
Median (95% CI) white blood cells (/mm3)*12700 (11400 to 14200)11600 (10000 to 13030)0.09
Range2600–490002700–63000
Ascites (%)77.5%75.6%0.69
Encephalopathy (%)45.3%38%0.17
  • * Biological characteristics are provided on the first day of treatment.

  • AST, aspartate aminotransferase.