Table 3

Change in laboratory tests in corticosteroid and non-corticosteroid groups at days 7, 14 and 28 of treatment

Patients allocated to the non-corticosteroid groupPatients allocated to the corticosteroid groupp Value
Bilirubin difference between day 0 and day 7 (μmol/l)0.002
No of patients148176
Median (95% CI)28.05 (18.7 to 44.2)61.6 (47.6 to 78.3)
Lille model score0.002
No of patients148176
Median (95% CI)0.365 (0.266 to 0.495)0.215 (0.144 to 0.306)
Bilirubin at day 7 (μmol/l)0.008
No of patients148176
Median (95% CI)255.9 (215.9 to 299)188 (160 to 213)
Albumin at day 7 (g/l)<0.00001
No of patients139165
Median (95% CI)24.1 (23 to 26)28 (26 to 29)
Prothrombin time at day 7 (s)0.02
No of patients98114
Median (95% CI)16.5 (16 to 17)16 (16 to 16.5)
Bilirubin at day 14 (μmol/l)0.01
No of patients113152
Median (95% CI)193.8 (158.1 to 236)147.05 (117.3 to 169)
Albumin at day 14 (g/l)0.0001
No of patients102148
Median (95% CI)26 (24.7 to 26)28 (26.9 to 29.8)
Bilirubin at day 28 (μmol/l)0.007
No of patients85113
Median (95% CI)107 (76.5 to 131)74.8 (62.9 to 93)
Albumin at day 28 (g/l)0.02
No of patients78108
Median (95% CI)27.35 (26 to 29.4)30.25 (29 to 31)
Prothrombin time at day 28 (s)0.18
No of patients81107
Median (95% CI)15.1 (14.6 to 16)15 (14 to 16)