Immunohistochemical analysis of the different lesions in liver needle biopsies
| LRN | HA | FNH | DN | WD HCC | MD HCC | PD HCC | |
| n=6 | n=6 | n=20 | n=25 | n=18 | n=37 | n=17 | |
| All three positive | 0 | 0 | 0 | 0 | 4 | 16 | 6 |
| At least two positive | 0 | 0 | 0 | 0 | 11 | 32 | 15 |
| At least one positive | 0 | 0 | 2 | 7 | 16 | 37 | 17 |
| EZH2+/HSP70+ | 0 | 0 | 0 | 0 | 7 | 22 | 8 |
| EZH2+/GPC3+ | 0 | 0 | 0 | 0 | 6 | 21 | 10 |
| HSP70+/GPC3+ | 0 | 0 | 0 | 0 | 6 | 21 | 9 |
| EZH2+ | 0 | 0 | 1 | 3 | 12 | 31 | 13 |
| HSP70+ | 0 | 0 | 1 | 2 | 10 | 28 | 11 |
| GPC3+ | 0 | 0 | 0 | 2 | 9 | 26 | 14 |
DN, dysplastic nodule; FNH, focal nodular hyperplasia; HA, hepatocellular adenoma; LRN, large regenerative nodule; MD HCC, moderately differentiated hepatocellular carcinoma; PD HCC, poorly differentiated hepatocellular carcinoma; WD HCC, well-differentiated hepatocellular carcinoma.