Characteristics | Men | Women | p Value |
n | 720 | 470 | |
Age, years | 57.9±8.6 | 57.3±9.2 | 0.27 |
Smoking status (%): | |||
Non-smoker | 49.2 | 83.4 | <0.0001 |
Past smoker | 31.1 | 6.4 | |
Current smoker | 19.7 | 10.2 | |
Alcohol consumption, glasses/week | 2.7±4.4 | 1.2±3.1 | <0.0001* |
BMI, kg/m2 | 26.5±3.7 | 26.3±4.3 | 0.50 |
BMI (%): | |||
<25 kg/m2 | 35.2 | 40.2 | 0.006 |
25–29.9 kg/m2 | 49.4 | 40.2 | |
≥30 kg/m2 | 15.4 | 19.6 | |
Waist circumference, cm | 92.5±9.9 | 84.2±10.9 | <0.0001 |
SBP, mm Hg | 133.9±14.9 | 128.5±15.7 | <0.0001 |
DBP, mm Hg | 81.0±9.1 | 78.0±9.8 | <0.0001 |
Fasting glucose, mmol/l† | 5.75 (5.66 to 5.84) | 5.32 (5.22 to 5.43) | <0.0001 |
Triglycerides, mmol/l† | 1.22 (1.18 to 1.27) | 1.01 (0.96 to 1.05) | <0.0001 |
Total cholesterol, mmol/l | 5.34±1.03 | 5.53±0.99 | 0.001 |
HDL-cholesterol, mmol/l | 1.29±0.33 | 1.55±0.38 | <0.0001 |
LDL-cholesterol, mmol/l | 3.42±0.89 | 3.46±0.84 | 0.41 |
GGT, UI/l† | 32.0 (30.4 to 33.7) | 18.8 (17.7 to 20.1) | <0.0001 |
ALT, UI/l† | 25.4 (24.6 to 26.3) | 18.7 (18.0 to 19.5) | <0.0001 |
MCV, fl | 88.7±6.1 | 87.7±6.0 | 0.003 |
Platelets, 109/l | 240±55 | 266±62 | <0.0001 |
Metabolic syndrome (%) | 20.6 | 20.0 | 0.82 |
LSM, kPa, median (min–max) | 5.7 (1.8–35) | 4.9 (2.4–20.7) | <0.0001 |
LSM (%): | |||
<8.0 kPa | 90.6 | 95.5 | 0.001 |
≥8.0 kPa | 9.4 | 4.5 |
Data are means±SD or percentages unless otherwise specified.
↵* Test on ranks.
↵† Data are geometric means (95% CI) due to skewed distribution.
ALT, alanine aminotransferase; BMI, body mass index; DBP, diastolic blood pressure; GGT, γ-glutamyltranspeptidase; HDL, high-density lipoprotein; LDL, low-density lipoprotein; LSM, liver stiffness measurement; MCV, mean corpuscular volume; SBP, systolic blood pressure.