Table 7

Liver histological findings according to LSM, clinical and biological data and causes of liver disease

LSM values (kPa)SexAge (years)BMI (kg/m2)GGT (ULN)ALT (ULN)Platelet count (109/l)Causes of liver diseaseFibrosis score*Activity scoreSteatosis (%)
8 ≤LSM >13 (n=18)
 8M73311.21248NAFLDF1A0<10
 8.1M60273.51276ALDF1A0<10
 8.2F58291.11.2204PBCF2A110–30
 8.6M57271.11364NAFLDF1A010–30
 8.6M48281.21.3155NAFLDF1A110–30
 8.6M561811268ALDF1A10
 8.9M53281.11.2230NAFLDF2A130–60
 10.0M743011344ALDF2A210–30
 10.2M50441.51.25283NAFLDF0A010–30
 10.3M702811219NAFLDF2A210–30
 10.3M503413241NAFLDF1A1>60
 10.6M55294.21.7171ALDF1A130–60
 10.6M442611156HBVF1A1<10
 10.7M643511198HBVF2A130–60
 10.7M66302.62.2299HCVF2A210–30
 10.7M5220132174ALDF2A1>60
 10.9M66201.21177ALDF2A030–60
 11.8M71341.52272NAFLDF2A1>60
LSM ≥13 (n=9)
 13.7M782711188HCVF4A10
 15.5M69231.11348ALDF4A110–30
 16.3M74235.41143ALDF4A1<10
 17.6M74295.43.8170HCVF4A210–30
 20.7F71316.73237ALDF4A210–30
 21.3M583245.4176HCVF4A310–30
 24.8M652444.4151HBVF4A1<10
 25.7M71271.61.150ALDF4A1<30
 35.0M612126.51.1104ALDF4A110–30
  • Data on 27 individuals undergoing liver biopsy out of 89 subjects with LSM ≥8 kPa.

  • * According to the Metavir score in the case of viral hepatitis and to the Brunt score in the case of NAFLD or ALD.

  • ALD, alcoholic liver disease; ALT, alanine aminotransferase; BMI, body mass index; GGT, γ-glutamyltranspeptidase; HBV, hepatitis B virus; HCV, hepatitis C virus; LSM, liver stiffness measurement; NAFLD, non-alcoholic fatty liver disease; PBC, primary biliary cirrhosis; ULN, upper limit of normal values.