Additional adjustments for association between HDL-cholesterol and colon cancer risk
| Model | Continuous¶ |
| Per 1 SD increase | |
| Adjusted* | 0.78 (0.68 to 0.89) |
| Adjusted† | 0.77 (0.61 to 0.97) |
| Adjusted† + all biomarkers‡ | 0.80 (0.62 to 1.02) |
| Adjusted† + 4 factors metabolic syndrome§ | 0.75 (0.59 to 0.97) |
| Adjusted† + all biomarkers‡ + 4 factors metabolic syndrome§ | 0.77 (0.59 to 1.00) |
↵* Conditioned on matching factors and adjusted for height, weight, smoking habits, physical activity, education, consumption of fruit, vegetables, meat, fish and alcohol, intake of fibre, energy from fat and energy from non-fat; N cases/controls=612/612.
↵† Conditioned on matching factors and adjusted for height, weight, smoking habits, physical activity, education, consumption of fruit, vegetables, meat, fish and alcohol, intake of fibre, energy from fat and energy from non-fat; after removing all cases and controls with missing data for the additional confounders; N cases/controls=235/235.
↵‡ Included in ‘all biomarkers’ are blood concentrations of C reactive protein, glycosylated haemoglobin, C peptide and reactive oxygen metabolites.
↵§ Included in ‘4 factors metabolic syndrome’ are waist circumference, triglycerides, blood pressure and diabetes mellitus.
↵¶ Increases in 1 SD in HDL-cholesterol were 16.6 mg/dl.