Table 3

Multivariable analyses showing the odds of death within 30 days of surgery

CharacteristicComplete case analysis*Multiple imputation analysis
OR(95% CI)p ValueOR(95% CI)p Value
Age at diagnosis (per year)1.08(1.07 to 1.08)<0.0011.08(1.08 to 1.08)<0.001
Year of diagnosis (per advancing year)0.99(0.98 to 1.00)<0.0010.97(0.97 to 0.98)<0.001
Sex
 Male1.00<0.0011.00<0.001
 Female0.81(0.77 to 0.85)0.83(0.79 to 0.86)
Operation
 Elective1.00<0.0011.00<0.001
 Emergency2.61(2.46 to 2.77)2.67(2.53 to 2.82)
Dukes' stage at diagnosis
 A1.00<0.0011.00<0.001
 B1.28(1.17 to 1.4)1.23(1.12 to 1.35)
 C1.53(1.39 to 1.68)1.54(1.40 to 1.69)
 D2.63(2.37 to 2.93)2.50(2.24 to 2.78)
IMD income category
 Most affluent1.00<0.0011.00<0.001
 21.04(0.96 to 1.12)1.03(0.96 to 1.10)
 31.13(1.05 to 1.22)1.11(1.04 to 1.19)
 41.24(1.15 to 1.34)1.22(1.13 to 1.30)
 Most deprived1.37(1.26 to 1.49)1.32(1.23 to 1.42)
Cancer site
 Colon1.00<0.0011.000.0021
 Rectosigmoid0.83(0.76 to 0.91)0.88(0.82 to 0.96)
 Rectum0.92(0.86 to 0.98)0.94(0.89 to 0.99)
Charlson comorbidity score
 01.00<0.0011.00<0.001
 12.12(1.99 to 2.26)2.05(1.94 to 2.18)
 22.46(2.26 to 2.68)2.43(2.25 to 2.62)
 ≥34.51(4.06 to 5.01)4.38(3.98 to 4.82)
  • * Analyses based on only those individuals for whom all case-mix variables were available (n=136 105).

  • Analyses based on all individuals with missing case-mix data being imputed (n=160 290).

  • IMD, Index of Multiple Deprivation.