Week 20 maintained at week 24 | |||||
<20% reduction in PV | 20–39% reduction in PV | 40–99% reduction in PV | 100% reduction in PV | ||
Week 16 maintained to week 20 | <20% reduction in PV | 0 | 1 | 2 | 3 |
20–39% reduction in PV | 0 | 2 | 3 | 4 | |
>40% reduction in PV | 0 | 3 | 4 | 5 |
The criterion values relied on the timing and reduction from baseline in weekly parenteral volumes (PV). The protocol-defined reduction was set at a minimum of 20% and a maximum of 100%. The timing of onset and the duration of response incorporated the responses at week 16 maintained to week 20 and week 20 maintained at week 24.